The major cationic osmolyte of the ecf is sodium with negligible contributions from potassium, calcium, and magnesium. Body fluid composition american academy of pediatrics. Body fluid compartment volumes and compositions before drug administration. Show full abstract ecf are calculated while the volume of ecf is assessed clinically. Pdf chapter28 electrolyte and water balance researchgate. The functional ecf is more important when considering the effects of acute fluid interventions and the ratio of icf to functional ecf is 55. Most of it, 28 liters, is inside cells, in the intracellular compartment, and 14 liters is outside of cells, in the extracellular compartment.
Intracellular and extracellular compartments youtube. The compositions of the two components of the ecf plasma and ifare more similar to each other than either is to the icf figure. Hence her icf volume would have been 20 litres and her ecf volume would have been 10 litres 9. Ionics eg 82br, 35 so4, chloride isotopes crystalloids eg inulin, mannitol the ionic tracers are small and distribute throughout the ecf but there is some entry into cells. Physiology, water balance statpearls ncbi bookshelf. Normal distribution of body fluid is important for maintaining health through the balance of water metabolism. The distinction between icf and ecf is clear and is easy to understand.
Hypernatremia and hyponatremia can be associated with conditions of high, low, or normal ecf sodium and volume. The crystalloids are larger and less diffusable throughout the. Table 751 summarizes the composition of commonly used iv solutions and their respective distribution into the ecf and icf compartments. Composition of body fluids body fluids contain water and solids. Similar composition to isf thoracic duct lymph contains more protein than usual isf from liver. The composition of intracellular and extracellular fluid differs by the presence of high concentration of sodium ions and low concentration of potassium ions in the extracellular fluid.
The extracellular fluid is secreted by cells in different tissues to maintain a constant environment in the cell surroundings, aiding the cellular operations of that particular tissue. Physiology multiple choice question bank primary exam for fanzca july 2001 update. Because these fluids are outside of cells, these fluids are also considered components of the ecf compartment. Body compartment volumes and composition after giving a. The major anionic osmolyte of the ecf is chloride with important but minor contributions from bicarbonate and negativelycharged plasma proteins. However, various clinical pathologies can alter the fluid composition and. The remaining parts of the ecf are called the functional ecf. Click card to see definition tap card to see definition ecf. Both conditions are most commonly the result of abnormalities of water metabolism. Ecficf volume was measured by segmental multifrequency bioimpedance analysis.
The compositions of the two components of the ecfplasma and ifare more similar to each other than either is to the icf figure. The compositions of the two components of the ecfplasma and ifare more similar to each other than either is to the icf. Pdf association between the content of intracellular and. How to measure the fluid volume intra and extra cellular total body water constitutes in men about 60% of body weight, in women 50% is divided into icf and ecf. The icf is separated from the extracellular fluid see below by the plasma. Blood plasma has high concentrations of sodium, chloride, bicarbonate, and protein. Extracellular fluidintracellular fluid volume ratio as a. Hemodialysis patients with high ecficf ratio are not only fluid.
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