The major anionic osmolyte of the ecf is chloride with important but minor contributions from bicarbonate and negativelycharged plasma proteins. Body fluids and fluid compartments simple book production. Difference between intracellular and extracellular fluid. Electrolyte homeostasis pharmacotherapy quick guide. Normal distribution of body fluid is important for maintaining health through the balance of water metabolism. However, various clinical pathologies can alter the fluid composition and. Most of it, 28 liters, is inside cells, in the intracellular compartment, and 14 liters is outside of cells, in the extracellular compartment. Pdf chapter28 electrolyte and water balance researchgate. The compositions of the two components of the ecfplasma and ifare more similar to each other than either is to the icf. Hypernatremia and hyponatremia can be associated with conditions of high, low, or normal ecf sodium and volume. The composition of intracellular and extracellular fluid differs by the presence of high concentration of sodium ions and low concentration of potassium ions in the extracellular fluid. The icf is separated from the extracellular fluid see below by the plasma.
Body fluid composition american academy of pediatrics. Intracellular and extracellular compartments youtube. Click card to see definition tap card to see definition ecf. Similar composition to isf thoracic duct lymph contains more protein than usual isf from liver. With picmonic, get your life back by studying less and remembering more. The compositions of the two components of the ecfplasma and ifare more similar to each other than either is to the icf figure.
Ecf is further divided into interstitial extravascular and bloodplasma intravascular compartments. Extracellular fluidintracellular fluid volume ratio as a. Physiology, water balance statpearls ncbi bookshelf. The compositions of the two components of the ecf plasma and ifare more similar to each other than either is to the icf figure. Because these fluids are outside of cells, these fluids are also considered components of the ecf compartment. Show full abstract ecf are calculated while the volume of ecf is assessed clinically. The crystalloids are larger and less diffusable throughout the. Body compartment volumes and composition after giving a. Ecficf volume was measured by segmental multifrequency bioimpedance analysis.
Body fluid compartment volumes and compositions before drug administration. The functional ecf is more important when considering the effects of acute fluid interventions and the ratio of icf to functional ecf is 55. The major cationic osmolyte of the ecf is sodium with negligible contributions from potassium, calcium, and magnesium. Physiology multiple choice question bank primary exam for fanzca july 2001 update. Pdf association between the content of intracellular and. Study flashcards on chemical composition of ecf and icf at. The remaining parts of the ecf are called the functional ecf. Composition of body fluids body fluids contain water and solids. The extracellular fluid is secreted by cells in different tissues to maintain a constant environment in the cell surroundings, aiding the cellular operations of that particular tissue. Blood plasma has high concentrations of sodium, chloride, bicarbonate, and protein. Perioperative electrolyte and fluid balance oxford academic journals. Both conditions are most commonly the result of abnormalities of water metabolism. How to measure the fluid volume intra and extra cellular total body water constitutes in men about 60% of body weight, in women 50% is divided into icf and ecf. Table 751 summarizes the composition of commonly used iv solutions and their respective distribution into the ecf and icf compartments.
Hemodialysis patients with high ecficf ratio are not only fluid. Hence her icf volume would have been 20 litres and her ecf volume would have been 10 litres 9. The distinction between icf and ecf is clear and is easy to understand. Ionics eg 82br, 35 so4, chloride isotopes crystalloids eg inulin, mannitol the ionic tracers are small and distribute throughout the ecf but there is some entry into cells.
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